diff --git a/lib/tokenize.cpp b/lib/tokenize.cpp
index 0436d8517..cc8ae10e3 100644
--- a/lib/tokenize.cpp
+++ b/lib/tokenize.cpp
@@ -6599,7 +6599,9 @@ bool Tokenizer::simplifyRedundantParenthesis()
             }
         }
 
-        while (Token::Match(tok->previous(), "[{([,:] ( !!{") && Token::Match(tok->link(), ") [;,])]")) {
+        while (Token::Match(tok->previous(), "[{([,:] ( !!{") &&
+               Token::Match(tok->link(), ") [;,])]") &&
+               !Token::findmatch(tok, ",",tok->link())) {
             // We have "( ... )", remove the parenthesis
             tok->link()->deleteThis();
             tok->deleteThis();
diff --git a/test/testtokenize.cpp b/test/testtokenize.cpp
index e2eec9b3c..a2e75d4b9 100644
--- a/test/testtokenize.cpp
+++ b/test/testtokenize.cpp
@@ -4942,6 +4942,9 @@ private:
         ASSERT_EQUALS("a = b ? c : 123 ;", tokenizeAndStringify("a = b ? c : (123);", false));
         ASSERT_EQUALS("a = b ? c : 579 ;", tokenizeAndStringify("a = b ? c : ((123)+(456));", false));
         ASSERT_EQUALS("a = b ? 123 : c ;", tokenizeAndStringify("a = b ? (123) : c;", false));
+
+        // #4316
+        ASSERT_EQUALS("a = b ? c : ( d = 1 , 0 ) ;", tokenizeAndStringify("a = b ? c : (d=1,0);", false));
     }
 
     void tokenize_double() {