diff --git a/src/shrpx_connection.cc b/src/shrpx_connection.cc
index 34bc7c01..226ecfaf 100644
--- a/src/shrpx_connection.cc
+++ b/src/shrpx_connection.cc
@@ -43,13 +43,13 @@ using namespace nghttp2;
 
 namespace shrpx {
 
-#if !OPENSSL_101_API
+#if !OPENSSL_1_1_API
 
 void *BIO_get_data(BIO *bio) { return bio->ptr; }
 void BIO_set_data(BIO *bio, void *ptr) { bio->ptr = ptr; }
 void BIO_set_init(BIO *bio, int init) { bio->init = init; }
 
-#endif // !OPENSSL_101_API
+#endif // !OPENSSL_1_1_API
 
 Connection::Connection(struct ev_loop *loop, int fd, SSL *ssl,
                        MemchunkPool *mcpool, ev_tstamp write_timeout,
@@ -238,14 +238,14 @@ long shrpx_bio_ctrl(BIO *b, int cmd, long num, void *ptr) {
 
 namespace {
 int shrpx_bio_create(BIO *b) {
-#if OPENSSL_101_API
+#if OPENSSL_1_1_API
   BIO_set_init(b, 1);
-#else  // !OPENSSL_101_API
+#else  // !OPENSSL_1_1_API
   b->init = 1;
   b->num = 0;
   b->ptr = nullptr;
   b->flags = 0;
-#endif // !OPENSSL_101_API
+#endif // !OPENSSL_1_1_API
   return 1;
 }
 } // namespace
@@ -256,17 +256,17 @@ int shrpx_bio_destroy(BIO *b) {
     return 0;
   }
 
-#if !OPENSSL_101_API
+#if !OPENSSL_1_1_API
   b->ptr = nullptr;
   b->init = 0;
   b->flags = 0;
-#endif // !OPENSSL_101_API
+#endif // !OPENSSL_1_1_API
 
   return 1;
 }
 } // namespace
 
-#if OPENSSL_101_API
+#if OPENSSL_1_1_API
 
 BIO_METHOD *create_bio_method() {
   auto meth = BIO_meth_new(BIO_TYPE_FD, "nghttpx-bio");
@@ -283,7 +283,7 @@ BIO_METHOD *create_bio_method() {
 
 void delete_bio_method(BIO_METHOD *bio_method) { BIO_meth_free(bio_method); }
 
-#else // !OPENSSL_101_API
+#else // !OPENSSL_1_1_API
 
 BIO_METHOD *create_bio_method() {
   static BIO_METHOD shrpx_bio_method = {
@@ -297,7 +297,7 @@ BIO_METHOD *create_bio_method() {
 
 void delete_bio_method(BIO_METHOD *bio_method) {}
 
-#endif // !OPENSSL_101_API
+#endif // !OPENSSL_1_1_API
 
 void Connection::set_ssl(SSL *ssl) {
   tls.ssl = ssl;
diff --git a/src/shrpx_ssl.cc b/src/shrpx_ssl.cc
index be7c57e8..62fed907 100644
--- a/src/shrpx_ssl.cc
+++ b/src/shrpx_ssl.cc
@@ -72,13 +72,13 @@ namespace shrpx {
 
 namespace ssl {
 
-#if !OPENSSL_101_API
+#if !OPENSSL_1_1_API
 namespace {
 const unsigned char *ASN1_STRING_get0_data(ASN1_STRING *x) {
   return ASN1_STRING_data(x);
 }
 } // namespace
-#endif // !OPENSSL_101_API
+#endif // !OPENSSL_1_1_API
 
 namespace {
 int next_proto_cb(SSL *s, const unsigned char **data, unsigned int *len,
@@ -280,11 +280,11 @@ int tls_session_new_cb(SSL *ssl, SSL_SESSION *session) {
 
 namespace {
 SSL_SESSION *tls_session_get_cb(SSL *ssl,
-#if OPENSSL_101_API
+#if OPENSSL_1_1_API
                                 const unsigned char *id,
-#else  // !OPENSSL_101_API
+#else  // !OPENSSL_1_1_API
                                 unsigned char *id,
-#endif // !OPENSSL_101_API
+#endif // !OPENSSL_1_1_API
                                 int idlen, int *copy) {
   auto conn = static_cast<Connection *>(SSL_get_app_data(ssl));
   auto handler = static_cast<ClientHandler *>(conn->data);
diff --git a/src/ssl.cc b/src/ssl.cc
index 0dc34ff7..c2930fc9 100644
--- a/src/ssl.cc
+++ b/src/ssl.cc
@@ -54,13 +54,13 @@ const char *const DEFAULT_CIPHER_LIST =
     "SHA256:AES256-GCM-SHA384:AES128-SHA256:AES256-SHA256:AES128-SHA:AES256-"
     "SHA:DES-CBC3-SHA:!DSS";
 
-#if OPENSSL_101_API
+#if OPENSSL_1_1_API
 
 // CRYPTO_LOCK is deprecated as of OpenSSL 1.1.0
 LibsslGlobalLock::LibsslGlobalLock() {}
 LibsslGlobalLock::~LibsslGlobalLock() {}
 
-#else // !OPENSSL_101_API
+#else // !OPENSSL_1_1_API
 
 namespace {
 std::vector<std::mutex> ssl_global_locks;
@@ -91,7 +91,7 @@ LibsslGlobalLock::LibsslGlobalLock() {
 
 LibsslGlobalLock::~LibsslGlobalLock() { ssl_global_locks.clear(); }
 
-#endif // !OPENSSL_101_API
+#endif // !OPENSSL_1_1_API
 
 const char *get_tls_protocol(SSL *ssl) {
   switch (SSL_version(ssl)) {
@@ -166,9 +166,9 @@ bool check_http2_requirement(SSL *ssl) {
 void libssl_init() {
 // OPENSSL_config() is not available in BoringSSL.  It is also
 // deprecated as of OpenSSL 1.1.0.
-#if !defined(OPENSSL_IS_BORINGSSL) && !OPENSSL_101_API
+#if !defined(OPENSSL_IS_BORINGSSL) && !OPENSSL_1_1_API
   OPENSSL_config(nullptr);
-#endif // !defined(OPENSSL_IS_BORINGSSL) && !OPENSSL_101_API
+#endif // !defined(OPENSSL_IS_BORINGSSL) && !OPENSSL_1_1_API
 
   SSL_load_error_strings();
   SSL_library_init();
diff --git a/src/ssl_compat.h b/src/ssl_compat.h
index c81b8c3b..41424c2c 100644
--- a/src/ssl_compat.h
+++ b/src/ssl_compat.h
@@ -26,7 +26,7 @@
 
 #include <openssl/opensslv.h>
 
-#define OPENSSL_101_API                                                        \
+#define OPENSSL_1_1_API                                                        \
   (!defined(LIBRESSL_VERSION_NUMBER) && OPENSSL_VERSION_NUMBER >= 0x1010000fL)
 
 #endif // OPENSSL_COMPAT_H
diff --git a/src/util.cc b/src/util.cc
index 7a3646d3..fdbb8390 100644
--- a/src/util.cc
+++ b/src/util.cc
@@ -1351,7 +1351,7 @@ uint32_t hash32(const StringRef &s) {
   return h;
 }
 
-#if !OPENSSL_101_API
+#if !OPENSSL_1_1_API
 namespace {
 EVP_MD_CTX *EVP_MD_CTX_new(void) { return EVP_MD_CTX_create(); }
 } // namespace
@@ -1359,7 +1359,7 @@ EVP_MD_CTX *EVP_MD_CTX_new(void) { return EVP_MD_CTX_create(); }
 namespace {
 void EVP_MD_CTX_free(EVP_MD_CTX *ctx) { EVP_MD_CTX_destroy(ctx); }
 } // namespace
-#endif
+#endif // !OPENSSL_1_1_API
 
 int sha256(uint8_t *res, const StringRef &s) {
   int rv;